What type of filament? Acetone doesn’t do much to things like pla or petg, stuff that works aren’t things you generally want around the house, industrial solvents and stuff. The jar of acetone can soften it up some but you’ll need to soak for some time, I’ve used MEK too, but that’s in the “don’t keep that at home” category, it’s really flammable and should use ppe (I mean should use ppe for a lot of the stuff we use, 99% IPA is harsh on your skin, I use nitriles because it irritates my hands something fierce.)

Cold pull as others recommended, nozzles are consumables, def should keep some around. Cleaning filament works pretty well in my experience if you have a partial clog.

I’ve been there though, first block I didn’t use a sock and the set screws got encased in degraded petg, I ended up scrapping it and putting it on the shelf as a learning moment, def recommend a sock if you don’t have, it’s saved me a lot of grief.